Yes. EasyRoutes treats wholesale orders like any other Shopify orders for routing, dispatch, tracking, and proof of delivery. Ensure each record includes a valid shipping address; if not, correct it on the Shopify order (recommended) or add the address details to the stop in EasyRoutes. You can filter B2B orders by tags or other attributes when building a batch.
See: Working with items & fulfillments · Add a missing shipping address